{"id":273,"date":"2024-11-14T10:00:00","date_gmt":"2024-11-14T10:00:00","guid":{"rendered":"https:\/\/cninmed.com\/en\/?p=273"},"modified":"2025-09-18T12:52:26","modified_gmt":"2025-09-18T12:52:26","slug":"china-bd-2024-biotheus-and-biontech-enters-an-acquisition-on-pd-l1-vegf-a-bsabs-pm8002-bnt327","status":"publish","type":"post","link":"https:\/\/cninmed.com\/en\/2024\/273.html","title":{"rendered":"[China BD 2024] [China Biotech M&amp;A]\u00a0Biotheus and BioNTech Enters an Acquisition on PD-L1\/VEGF-A BsAbs PM8002 (BNT327)"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">Announced Date: 2024-11-13 (November 13, 2024)<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Licensor (Seller): Zhuhai Biotheus Inc (China)<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Licensee (Buyer): BioNTech<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Key Asset: PM8002 (BNT327)<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Asset Modality: BsAbs (Bispecific antibody)<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Asset Target: PD-L1 and VEGF-A<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Potential Indication: advanced solid tumors<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Scope of Authority:<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Under the agreement of 2024,<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">With the acquisition, BioNTech will obtain full global rights to the late-stage clinical asset BNT327\/PM8002, an investigational bispecific antibody targeting PD-L1 and VEGF-A. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Upon closing, BioNTech will gain full rights to Biotheus\u2019 pipeline candidates and its in-house bispecific antibody drug conjugate capability. The acquisition will expand BioNTech\u2019s footprint in China, adding a local research and development hub to conduct clinical trials. In addition, BioNTech will gain a state-of-the-art biologics manufacturing facility to contribute to its future global manufacturing and supply, and more than 300 Biotheus employees in R&amp;D, manufacturing and enabling functions are expected to join the BioNTech workforce.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Payment Detail:<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">BioNTech will pay Biotheus shareholders<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">an upfront consideration of $800 million, predominantly in cash, <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">plus additional performance-based contingent payments of up to $150 million if certain milestones are met. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Link:<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">. <a href=\"https:\/\/investors.biontech.de\/news-releases\/news-release-details\/biontech-acquire-biotheus-boost-oncology-strategy\/\">BioNTech to Acquire Biotheus to Boost Oncology Strategy | BioNTech<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">. <a href=\"https:\/\/investors.biontech.de\/news-releases\/news-release-details\/biontech-completes-acquisition-biotheus\">BioNTech Completes Acquisition of Biotheus | BioNTech<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">. <a href=\"https:\/\/cninmed.com\/en\/2023\/271.html\">[China BD 2023] Biotheus and BioNTech Enters the License on PD-L1\/VEGF-A BsAbs PM8002 (BNT327) \u2013 CninMed \u2013 China Innovative Drugs Update<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">. <a href=\"https:\/\/www.prnewswire.com\/news-releases\/biotheus-enters-into-strategic-partnership-with-biontech-to-develop-and-commercialize-bispecific-antibody-candidate-targeting-pd-l1-and-vegf-in-multiple-solid-tumor-indications-301978246.html\">Biotheus Enters Into Strategic Partnership with BioNTech to Develop and Commercialize Bispecific Antibody Candidate Targeting PD-L1 and VEGF in Multiple Solid Tumor Indications (prnewswire.com)<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Chinese Name of Biotheus, \u666e\u7c73\u65af<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Announced Date: 2024-11-13 (November 13, 2024) Licensor (Seller): Zhuhai Biotheus Inc (China) Licensee (Buyer): BioNTech . &hellip; <a title=\"[China BD 2024] [China Biotech M&amp;A]\u00a0Biotheus and BioNTech Enters an Acquisition on PD-L1\/VEGF-A BsAbs PM8002 (BNT327)\" class=\"hm-read-more\" href=\"https:\/\/cninmed.com\/en\/2024\/273.html\"><span class=\"screen-reader-text\">[China BD 2024] [China Biotech M&amp;A]\u00a0Biotheus and BioNTech Enters an Acquisition on PD-L1\/VEGF-A BsAbs PM8002 (BNT327)<\/span>Read more<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10,1],"tags":[],"class_list":["post-273","post","type-post","status-publish","format-standard","hentry","category-china-biotech-ma","category-china-license-out"],"_links":{"self":[{"href":"https:\/\/cninmed.com\/en\/wp-json\/wp\/v2\/posts\/273","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cninmed.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cninmed.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cninmed.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cninmed.com\/en\/wp-json\/wp\/v2\/comments?post=273"}],"version-history":[{"count":3,"href":"https:\/\/cninmed.com\/en\/wp-json\/wp\/v2\/posts\/273\/revisions"}],"predecessor-version":[{"id":361,"href":"https:\/\/cninmed.com\/en\/wp-json\/wp\/v2\/posts\/273\/revisions\/361"}],"wp:attachment":[{"href":"https:\/\/cninmed.com\/en\/wp-json\/wp\/v2\/media?parent=273"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cninmed.com\/en\/wp-json\/wp\/v2\/categories?post=273"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cninmed.com\/en\/wp-json\/wp\/v2\/tags?post=273"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}