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[Technology Collaboration] SanegeneBio and Lilly Enters a 1.2 billion USD Collaboration on RNAi Research for Metabolic Disease Targets

Announced Date: 2025-11-08 (November 08, 2025)

Licensor: SanegeneBio (China)

Licensee: Eli Lilly (US)

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Scope of Collaboration:

RNAi research for metabolic disease targets

Collaborate to advance RNAi candidates for metabolic diseases, based on SanegeneBio’s proprietary tissue selective delivery technology, LEAD™ (Ligand and Enhancer Assisted Delivery).

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SanegeneBio will be responsible for discovery and identification of the optimized LEAD™-based RNAi molecule for each program, while Lilly will be responsible for the subsequent IND-enabling studies, clinical development and commercialization.

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Deal Detail:

SanegeneBio will receive an upfront payment and equity investment and will be eligible to receive near-term milestone payments.

SanegeneBio will also be eligible to receive up to $1.2 billion in discovery, development, regulatory, and commercial milestone payments, as well as tiered royalties on future product sales.

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Link: 

SanegeneBio Announces RNAi Licensing and Research Collaboration with Lilly (prnewswire.com)

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Note:

Chinese Name of SanegeneBio, 圣因生物

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