[China BD 2024] Alphamab and ArriVent enters a 615.5 million USD License on two preclinical ADC assets, ARR-173 and ARR-421

Announced Date: 2024-06-05 (June 5, 2024)

Asset Name: Two ADC asset （ARR-173, ARR-421）

Licensor: Jiangsu Alphamab Biopharmaceuticals, the subsidiary of Alphamab Oncology (China)

Licensee (Buyer): Arrivent Biopharma, Inc (US)

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Asset Modality: antibody drug conjugate (ADC)

Asset Target: Undisclosed

Potential Indication: Treatment of cancers

Current Stage:  Preclinical

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Scope of Authority:

Alphamab and ArriVent will collaborate to use Alphamab’s proprietary linker-payload (Alphatecan) and glycan-conjugation platforms to discover and develop novel antibody drug conjugates (“ADC”).

Alphamab will retain the rights to develop and commercialize the related ADC products under the Collaboration Agreement, in mainland China, Hong Kong, Macau and Taiwan Region (collectively, the “Greater China Region”).

ArriVent will have exclusive rights to develop and commercialize the ADC products in the field of oncology in countries and regions outside of the Greater China Region and will be responsible for and bear the cost of the corresponding development of the ADC products.

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Payment Detail:

Combined upfront and potential milestone payments to Alphamab of up to $615.5 million.

Tiered sales royalties from ArriVent for each ADC product.

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Link:

ArriVent Announces a Multi-Target ADC Collaboration with Alphamab – ArriVent Biopharma

Alphamab Oncology Collaborated with ArriVent in relation to the Research, Development and Commercialization of ADC Products-Alphamab Oncology

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Note:

Chinese Name of “Alphamab“，康宁杰瑞