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[China BD 2022] Jemincare and Genentech (Roche) enters a 650 million USD license on AR degrader JMKX002992 (RG6537, GDC-2992)

Announced Date: 2022-08-05 (August 18, 2025)

Asset Name: JMKX002992 (RG6537, GDC-2992)

Licensor: Shanghai Jemincare Pharmaceutical (China)

Licensee (Buyer): Genentech, member of Roche Group

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Asset Modality: Small Molecule, oral degrader

Asset Target: Androgen receptor (AR) degrader

Potential Indication: prostate cancer

Current Stage:

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Scope of Authority:

Jemincare will grant Genentech the exclusive license to develop and commercialize the degrader worldwide, and will be fully responsible for the development and commercialization costs.

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Payment Detail:

Jemincare will receive:

Upfront payment of $60 million,

Regulatory and sales milestone payments up to  $590 million.

Tiered royalties on net sales.

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Link:

Jemincare Announces Exclusive License Agreement with Genentech to Develop and Commercialize Novel Oral Androgen Receptor Degrader

https://www.jemincare.com/news/detail.html?id=94

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Note:

Chinese Name of Jemincare 济民可信

Chinese Name of Shanghai Jemincare Pharmaceutical 上海济煜

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