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[China BD 2025] Evopoint and Astellas enters a 1.54 billion USD license on CLDN18.2 ADC XNW27011

Announced Date: 2025-05-29 (May 29, 2025)

Asset Name: XNW27011

Licensor: Evopoint (Evopoint Biosciences Co., Ltd., China)

Licensee (Buyer): Astellas (Astellas Pharma Inc., Japan)

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Asset Modality: ADC (antibody drug conjugate) 

Asset Target: CLDN18.2

Potential Indication: solid tumors, including gastric cancer, gastroesophageal cancer and pancreatic cancer

Current Stage: Phase I/II, in China

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Scope of Authority:  

Evopoint has granted Astellas exclusive worldwide rights (excluding China’s mainland, Hong Kong, Macao and Taiwan region) to develop and commercialize XNW27011 .

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Deal Detail:

Upfront payment of $130 million,

Near-term payment up to $70 million,

Milestone payments up to  $1.34 billion.

Tiered royalties on net sales.

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Link:

Astellas Enters Exclusive License Agreement with Evopoint Biosciences for XNW27011, a Novel Clinical-stage Antibody-Drug Conjugate Targeting CLDN18.2 – May 29, 2025

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